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J Med Assoc Thai. 2011 Mar;94 Suppl 2:S66-70.

Prevalence of low birthweight infants in HIV-infected women delivered in Rajavithi Hospital.

Author information

1
Department of Obstetrics and Gynecology, Rajavithi Hospital, College of Medicine, Rangsit University, Bangkok, Thailand. asuvanna@yahoo.com

Abstract

OBJECTIVE:

To determine the prevalence of low birthweight infants in HIV-infected pregnant women delivered in Rajavithi Hospital and the relationship between antiretroviral drugs and low birthweight infants.

MATERIAL AND METHOD:

All numbers of low birthweight (LBW) infants and pregnant women with or without HIV infection delivered in Rajavithi Hospital during 2004-2008 from medical records were used. Two hundred HIV-infected pregnant women who delivered their infants at the same period were random for description and analysis.

RESULTS:

The prevalence of low birthweight infants delivered by HIV and non HIV-infected pregnant women were 12.6% (53/ 420) and 13.3% (4,249/31,975), respectively. There was no significant association between HIV infection and low birthweight (p = 0.688). Low birthweight infants delivered from HIV-infected pregnant women with and without antiretroviral therapy were 9.9% (7/41) and 13.6% (19/159), respectively. Various types of antiretroviral (ARV) drug including no ARV were significantly associated with LBW (p = 0.021). The one who received highly active antiretroviral therapy (HAART) had 2.27 times higher risk in having LBW.

CONCLUSION:

The prevalence of low birthweight infants among HIV-infected pregnant women was 12.6%. There was no association between HIV infection and LBW. HAART might be a risk of LBW.

PMID:
21717881
[Indexed for MEDLINE]

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