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J Assist Reprod Genet. 2011 Sep;28(9):809-14. doi: 10.1007/s10815-011-9603-z. Epub 2011 Jun 30.

Attitudes of Klinefelter men and their relatives towards TESE-ICSI.

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1
Department of Medical Genetics, University Medical Center Utrecht, Utrecht, The Netherlands. m.maiburg@umcutrecht.nl

Abstract

PURPOSE:

At the start of the implementation of TESE-ICSI for Klinefelter men in the Netherlands, we aimed to evaluate their wish to father children and their attitudes towards this artificial reproduction technique.

METHODS:

Questionnaires were distributed to members of the Dutch Klinefelter Association (nā€‰=ā€‰365) and to Klinefelter cases known at our Department (nā€‰=ā€‰58). Questions addressed several aspects: socio-demographic characteristics, ascertainment of diagnosis, children and child wish, and TESE-ICSI. Data were characterized using descriptive statistics.

RESULTS:

A total of 260 questionnaires (corresponding to 194 cases, 46%) were returned. A possible wish to father children was reported by 90% of Klinefelter men. 70% of Klinefelter men and 74% of their partners would (probably) opt for TESE-ICSI.

CONCLUSION:

The majority of Dutch Klinefelter men and their partners desire to have children and have a positive attitude towards TESE-ICSI. Concerns include the risk of congenital malformations/developmental delay of the child and the limited success rate of TESE-ICSI.

PMID:
21717174
PMCID:
PMC3169690
DOI:
10.1007/s10815-011-9603-z
[Indexed for MEDLINE]
Free PMC Article
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