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J Midlife Health. 2010 Jul;1(2):63-9. doi: 10.4103/0976-7800.76214.

Menopause and metabolic syndrome: A study of 498 urban women from western India.

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Medical Research Centre of Kasturba Health Society, ICMR Advanced Center of Reverse Pharmacology. 17, Khandubhai Desai Road, Vile Parle, Mumbai - 400 052, India.



Metabolic syndrome (MS) is a cluster of risk factors for future development of type 2 diabetes mellitus and cardiovascular diseases. Menopausal transition with its incidental hormonal changes is considered to contribute to the development of MS. However, age is known to influence MS risk factors.


The present study explores the prevalence of MS in pre- and postmenopausal women from western India.


Four hundred and ninety eight women above 35 years of age, participating in women's health care program were assessed for the prevalence of MS using two criteria- International Diabetes Federation criteria (IDF) and Harmonization (H_MS) criteria.


Prevalence of MS amongst postmenopausal women was significantly higher (P < 0.001) than that in premenopausal women by both, IDF (premenopausal 45% and postmenopausal 55%) and H_MS criteria (premenopausal 44% and postmenopausal 56%). However, this significance disappeared when data was adjusted for the confounding variable of age.


Indian women; International diabetes federation criteria; harmonization criteria; menopause; metabolic syndrome

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