Send to

Choose Destination
See comment in PubMed Commons below
J Neurosci. 2011 Jun 29;31(26):9658-64. doi: 10.1523/JNEUROSCI.0660-11.2011.

Is gamma-band activity in the local field potential of V1 cortex a "clock" or filtered noise?

Author information

Center for Neural Science and Courant Institute of Mathematical Sciences, New York University, New York 10012, USA.


Gamma-band (25-90 Hz) peaks in local field potential (LFP) power spectra are present throughout the cerebral cortex and have been related to perception, attention, memory, and disorders (e.g., schizophrenia and autism). It has been theorized that gamma oscillations provide a "clock" for precise temporal encoding and "binding" of signals about stimulus features across brain regions. For gamma to function as a clock, it must be autocoherent: phase and frequency conserved over a period of time. We computed phase and frequency trajectories of gamma-band bursts, using time-frequency analysis of LFPs recorded in macaque primary visual cortex (V1) during visual stimulation. The data were compared with simulations of random networks and clock signals in noise. Gamma-band bursts in LFP data were statistically indistinguishable from those found in filtered broadband noise. Therefore, V1 LFP data did not contain clock-like gamma-band signals. We consider possible functions for stochastic gamma-band activity, such as a synchronizing pulse signal.

[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for HighWire Icon for PubMed Central
    Loading ...
    Support Center