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PLoS One. 2011;6(6):e21513. doi: 10.1371/journal.pone.0021513. Epub 2011 Jun 21.

Vernalization-repression of Arabidopsis FLC requires promoter sequences but not antisense transcripts.

Author information

1
CSIRO Plant Industry, Canberra, Australia. chris.helliwell@csiro.au

Abstract

The repression of Arabidopsis FLC expression by vernalization (extended cold) has become a model for understanding polycomb-associated epigenetic regulation in plants. Antisense and sense non-coding RNAs have been respectively implicated in initiation and maintenance of FLC repression by vernalization. We show that the promoter and first exon of the FLC gene are sufficient to initiate repression during vernalization; this initial repression of FLC does not require antisense transcription. Long-term maintenance of FLC repression requires additional regions of the gene body, including those encoding sense non-coding transcripts.

PMID:
21713009
PMCID:
PMC3119698
DOI:
10.1371/journal.pone.0021513
[Indexed for MEDLINE]
Free PMC Article

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