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Int J Trichology. 2010 Jul;2(2):86-8. doi: 10.4103/0974-7753.77511.

Bimatoprost in the treatment of eyelash universalis alopecia areata.

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  • 1Universital Hospital Virgen Macarena, Sevilla, Spain.

Abstract

OBJECTIVES:

To evaluate topical bimatoprost for eyelash growth in patients with alopecia areata (AA).

DESIGN:

A 1-year retrospective study, bilateral eyelash alopecia.

MATERIALS AND METHODS:

Forty-one subjects with AA universalis without ocular disease applied 0.03% bimatoprost to the eyelid margin once a day over the course of 1 year.

RESULTS:

Thirty-seven subjects completed the study, one patient was eliminated due to conjunctivitis at the beginning of treatment, two patients developed conjunctivitis after 6 months of treatment, and a fourth did not follow directions. Researchers evaluated patients' eyelash growth every 4 months. We observed complete growth in 24.32%, moderate growth in 18.91%, slight growth in 27.02% and without response in 29.72%.

CONCLUSION:

Bimatoprost may be effective and safe in the treatment of eyelash AA. 43.24% of the patients had an acceptable cosmetic response (total and moderate growth).

LIMITATIONS:

Design without control.

KEYWORDS:

Alopecia areata; bimatoprost; eyelash growth; prostaglandins

PMID:
21712909
PMCID:
PMC3107964
DOI:
10.4103/0974-7753.77511
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