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Vector Borne Zoonotic Dis. 2011 Nov;11(11):1503-5. doi: 10.1089/vbz.2010.0169. Epub 2011 Jun 24.

Bartonella henselae infection of prosthetic aortic valve associated with colitis.

Author information

1
Division of Infectious Diseases, Department of Medicine, University of California San Diego, La Jolla, California, USA.

Abstract

The diagnosis of infective endocarditis can be difficult, particularly with atypical presentation and negative blood cultures. A 61-year-old man with a porcine aortic valve presented with fever, intermittent confusion, diarrhea, and fatigue. In the community clinic setting, a colonoscopy performed for anemia demonstrated colitis. Symptoms progressed for months; elicitation of a history of significant kitten exposure and the finding of an axillary lymph node prompted testing for Bartonella henselae antibodies. High titer antibodies by indirect immunofluorescence assay indicated chronic B. henselae infection. Surgical valve replacement followed by prolonged doxycycline and rifampin led to cure. This case illustrates the complexities of infective endocarditis and is the first description B. henselae endocarditis associated with colitis in an immunocompetent adult.

PMID:
21702667
PMCID:
PMC3216094
DOI:
10.1089/vbz.2010.0169
[Indexed for MEDLINE]
Free PMC Article

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