Should uterine tandem applicators ever be placed without ultrasound guidance? No: a brief report and review of the literature

Int J Gynecol Cancer. 2011 Jul;21(5):941-4. doi: 10.1097/IGC.0b013e31821bca53.

Abstract

Background: Brachytherapy is an integral component of the curative treatment of locally advanced cervical cancer. Optimal applicator placement is associated with improvements in local control and treatment-related toxicity. Uterine perforation by the tandem is common and often undetected by orthogonal radiographs. The role of ultrasound in guiding tandem placement remains controversial.

Methods: A 55-year-old woman with International Federation of Gynecology and Obstetrics stage IIB cervix cancer underwent placement of a Fletcher-Suit-Delcos tandem and ovoids applicator. Postoperative computed tomography was used for treatment planning.

Results: The applicator appeared to be appropriately placed on clinical exam and orthogonal radiographs. Postoperative computed tomography revealed the tandem had perforated the anterior uterine wall. In a second procedure, the tandem was placed correctly under intraoperative ultrasonography.

Conclusions: A review of the literature finds a relatively high rate of uterine perforation of the uterus that is undetected by orthogonal radiographs or clinical examination. Multiple reports support the use of real-time ultrasound for patients with especially challenging anatomy. As this report illustrates, uterine perforation is possible in any patient. Therefore, routine real-time ultrasonography should be considered for all uterine tandem insertions.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Brachytherapy / adverse effects*
  • Brachytherapy / instrumentation*
  • Brachytherapy / methods
  • Carcinoma, Squamous Cell / diagnostic imaging
  • Carcinoma, Squamous Cell / radiotherapy*
  • Female
  • Foreign-Body Migration / etiology
  • Foreign-Body Migration / prevention & control
  • Humans
  • Iatrogenic Disease / prevention & control
  • Middle Aged
  • Radiotherapy, Image-Guided / instrumentation
  • Radiotherapy, Image-Guided / methods*
  • Ultrasonography
  • Uterine Cervical Neoplasms / diagnostic imaging
  • Uterine Cervical Neoplasms / radiotherapy*
  • Uterine Perforation / etiology
  • Uterine Perforation / prevention & control
  • Uterus / diagnostic imaging*