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Ophthalmic Res. 2012;47(1):23-6. doi: 10.1159/000328629. Epub 2011 Jun 21.

Safety and efficacy of fibrin glue versus vicryl sutures in recurrent pterygium with amniotic membrane grafting.

Author information

1
Department of Ophthalmology, Faculty of Medicine, Zagazig University, Zagazig, Egypt. redaelmahdy2005@yahoo.com

Abstract

PURPOSE:

The study aimed to compare surgical outcomes with likely toxic side effects when using pterygium excision and amniotic membrane grafting with fibrin glue versus Vicryl sutures.

METHOD:

This is a prospective randomized study. Patients were classified into two groups: group 1 consisted of 20 patients with Vicryl-sutured grafts, and group 2 consisted of 20 patients with fibrin-glued grafts that were prepared from autologous blood. Results including surgery time, patient discomfort, complications and recurrence rates within 1, 6 and 12 months were analyzed.

RESULTS:

The study demonstrated that there was a statistically significant decrease in surgery time in the fibrin glue group (the procedure took 17 min) relative to the sutured group (28 min; p < 0.05). Additionally, both postoperative pain and discomfort were noted significantly less often in the fibrin glue group. Complications were also decreased in the fibrin glue group.

CONCLUSION:

The study revealed that the use of fibrin glue in pterygium surgery with amniotic membrane grafting was safer, less toxic and less time-consuming, and resulted in fewer complications than graft surgery with sutures.

PMID:
21691139
DOI:
10.1159/000328629
[Indexed for MEDLINE]

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