Format

Send to

Choose Destination
Front Microbiol. 2010 Dec 8;1:134. doi: 10.3389/fmicb.2010.00134. eCollection 2010.

A brief history of the antibiotic era: lessons learned and challenges for the future.

Author information

1
Rowett Institute of Nutrition and Health, University of Aberdeen Aberdeen, UK.

Abstract

This article gives a very brief overview of the antibiotic era, beginning from the discovery of first antibiotics until the present day situation, which is marred by the emergence of hard-to-treat multiple antibiotic-resistant infections. The ways of responding to the antibiotic resistance challenges such as the development of novel strategies in the search for new antimicrobials, designing more effective preventive measures and, importantly, better understanding the ecology of antibiotics and antibiotic resistance are discussed. The expansion of conceptual frameworks based on recent developments in the field of antimicrobials, antibiotic resistance, and chemotherapy is also discussed.

KEYWORDS:

antibiotic resistance; environmental resistome; history of antibiotic discovery; novel antimicrobials; prevention of antibiotic resistance

Supplemental Content

Full text links

Icon for Frontiers Media SA Icon for PubMed Central
Loading ...
Support Center