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BMJ Case Rep. 2009;2009. pii: bcr10.2008.1058. doi: 10.1136/bcr.10.2008.1058. Epub 2009 Mar 17.

Gastrointestinal lesions in parvovirus B19 infection.

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S.Orsola-Malpighi Hospital, University of Bologna, Department of Paediatrics, Via Massarenti 11, Bologna 40138, Italy.


A 13-year-old girl with persistent fever, pharyngitis, acute anaemia, peripheral blood and bone marrow positive for parvovirus B19 DNA.Microscopic findings of gastrointestinal biopsy showed diffuse vacuolar alteration of the cytoplasma of duodenal enterocytes and virological analysis demonstrated the presence of parvovirus in lymphocytes of the duodenal wall's epithelial layer.In unexplained gastrointestinal pathologies, the role of parvovirus B19 infection should be investigated.

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