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Med Clin North Am. 2011 Jul;95(4):677-702, vii. doi: 10.1016/j.mcna.2011.03.010.

Use of antibacterial agents in renal failure.

Author information

1
Division of Infectious Diseases, Department of Medicine, Thomas Jefferson University Hospital, Lankenau Hospital, Lankenau Medical Building, Suite 164, Wynnewood, PA 19096, USA. santorow@mlhs.org

Abstract

This article provides background information on the pharmacokinetics of antibacterial agents in patients who have normal and impaired renal function. Tables are provided to allow quick determination of appropriate dosages for varying degrees of renal failure. The use of serum levels; newer strategies for cefazolin, vancomycin and aminoglycoside dosing; methods of dialysis and associated antibiotics dosage adjustments, and antibiotic toxicity in renal failure are reviewed.

Republished from

PMID:
21679787
DOI:
10.1016/j.mcna.2011.03.010

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