Format

Send to

Choose Destination
J Med Virol. 2011 Aug;83(8):1406-9. doi: 10.1002/jmv.22109.

Positive Epstein-Barr virus and cytomegalovirus IgM assays in primary HIV infection.

Author information

1
Department of Infectious Diseases, Prince of Wales Hospital, Randwick, NSW, Australia. j.post@unsw.edu.au

Abstract

We report three cases with misleading cytomegalovirus (CMV) or Epstein-Barr virus (EBV) immunoglobulin M (IgM) results during primary human immunodeficiency virus (HIV) infection. We determined the rate of positive anti-CMV IgM assays or anti-EBV capsid antigen IgM assays in sera from a group of well-characterized subjects with primary HIV infection as 2.9% (1/35; 95%CI: 0.15-16.6%) for each infection. The rate of positive anti-EBV capsid antigen IgM assays in subjects with positive hepatitis A virus IgM assays was 30% (6/20; 95%CI: 14.6-51.9%). Clinicians need to consider the limitations of IgM assays for diagnosis of herpesvirus infections, and consider testing for other infections with overlapping clinical manifestations.

PMID:
21678445
DOI:
10.1002/jmv.22109
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Wiley
Loading ...
Support Center