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Cell. 2011 Jun 10;145(6):831-4. doi: 10.1016/j.cell.2011.05.034.

The human brain in a dish: the promise of iPSC-derived neurons.

Author information

1
Department of Neurobiology, Fairchild Research Building, Room D227, Stanford University, Stanford, CA 94305, USA. ricardo.dolmetsch@stanford.edu

Abstract

Induced pluripotent stem cell-derived neurons from patients promise to fill an important niche between studies in humans and model organisms in deciphering mechanisms and identifying therapeutic avenues for neurologic and psychiatric diseases. Recent work begins to tap this potential and also highlights challenges that must be overcome to be fully realized.

PMID:
21663789
PMCID:
PMC3691069
DOI:
10.1016/j.cell.2011.05.034
[Indexed for MEDLINE]
Free PMC Article
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