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J Am Psychiatr Nurses Assoc. 2011 Jan-Feb;17(1):51-6. doi: 10.1177/1078390310395586.

Does assertive community treatment increase medication adherence for people with co-occurring psychotic and substance use disorders?

Author information

1
Department of Psychiatry, College of Physicians and Surgeons, Columbia University and New York State Psychiatric Institute, New York, NY 10032, USA. jm703@columbia.edu

Abstract

OBJECTIVE:

This study analyzed data from a randomized trial to examine the impact on medication adherence of integrated treatment delivered via assertive community treatment (ACT) versus standard clinical case management (SCCM).

METHOD:

Data from the original study included 198 study participants with co-occurring psychotic and substance use disorders who were randomly assigned to receive integrated treatment via ACT or SCCM and were followed for 3 years. We applied mixed-effects logistic regression to estimate group (ACT vs. SCCM) by time effects on a self-report measure of medication adherence. Adherence was dichotomized as 20% or more missed medication days ("poor adherence") versus less than 20% missed medication days ("adequate adherence").

RESULTS:

Participants who were assigned to ACT reported significant improvement in medication adherence compared with those assigned to SCCM.

CONCLUSIONS:

Integrated treatment delivered via ACT may benefit persons with co-occurring psychotic and substance use disorders who are poorly adherent to medications.

PMID:
21659294
PMCID:
PMC4164343
DOI:
10.1177/1078390310395586
[Indexed for MEDLINE]
Free PMC Article
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