Mismatched transfusion of 8 AB0-incompatible units of packed red blood cells in a patient with acute intermittent porphyria

Saudi J Anaesth. 2011 Jan;5(1):101-4. doi: 10.4103/1658-354X.76497.

Abstract

We report on a patient with acute intermittent porphyria, who received 8 AB0 incompatible units of packed red blood cells in an emergency situation. She never showed any signs of severe intravascular haemolysis. The patient died after four weeks because of a multi-organ failure caused from the malpractice of the porphyria. The problems of bedside testing, mixing field reaction, fresh frozen plasma and molecular-genetic determination of bloodgroup were discussed.

Keywords: Incompatible transfusion; mixed field reaction; molecular genetic diagnostic; porphyria.

Publication types

  • Case Reports