Abstract
A previously-described herpes simplex virus type 2 DNA-binding protein with a molecular size of 38 kD has been further characterized. Using purified nucleocapsids, a DNase release assay, and intertypic recombinants, this protein was found to be a component of the nucleocapsid, intimately associated with the nuclear matrix, and encoded between 0.605 and 0.720 on the herpes simplex virus type 2 genome.
Publication types
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Research Support, U.S. Gov't, P.H.S.
MeSH terms
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Animals
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Capsid / analysis*
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Cells, Cultured
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Cricetinae
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DNA-Binding Proteins / analysis*
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DNA-Binding Proteins / genetics
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Electrophoresis, Polyacrylamide Gel
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Genes, Viral
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Immunoblotting
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Nuclear Matrix / microbiology
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Plasmids / genetics
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RNA, Messenger / genetics
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Simplexvirus / analysis*
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Vero Cells
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Viral Core Proteins / analysis*
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Viral Proteins / analysis*
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Viral Proteins / genetics
Substances
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DNA-Binding Proteins
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RNA, Messenger
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Viral Core Proteins
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Viral Proteins