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Bioessays. 1990 May;12(5):199-204.

Dissecting the complexity of the nervous system by enhancer detection.

Author information

1
Howard Hughes Medical Institute, Baylor College of Medicine, Houston, TX 77030.

Abstract

Enhancer detectors are DNA constructs which, when introduced into a eukaryotic genome, respond to nearby genomic transcriptional regulatory elements by means of a reporter gene, revealing the expression pattern of genes in their vicinity. Recent experiments in Drosophila suggest that enhancer detection is a powerful method to identify genes that are expressed in the nervous system. Since enhancer detectors allow a rapid molecular and genetic characterization of genes in their vicinity, the method will greatly facilitate the study of neural development and behavior.

PMID:
2164394
DOI:
10.1002/bies.950120502
[Indexed for MEDLINE]

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