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Methods Mol Biol. 2011;747:193-218. doi: 10.1007/978-1-61779-136-9_8.

LC/TOF-MS analysis of pesticides in fruits and vegetables: the emerging role of accurate mass in the unambiguous identification of pesticides in food.

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Center for Environmental Mass Spectrometry, Department of Environmental Engineering, University of Colorado, Boulder, CO, USA.


The detection, identification, confirmation, and quantitation of pesticides in fruits and vegetables are typically performed from a list of suspect compounds or targets. However, there is mounting concern that pesticides not targeted are finding their way into the food supply. This chapter describes the use of LC with time-of-flight mass spectrometry (LC/TOF-MS) for the detection and identification of pesticides that are not targeted. The use of accurate mass measurement and its implication for the identification of non-targeted compounds are discussed. The need for unambiguous identification and requirements therein are evaluated in detail.

[Indexed for MEDLINE]

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