Format

Send to

Choose Destination
See comment in PubMed Commons below
Acta Pharmacol Sin. 2011 Jun;32(6):741-8. doi: 10.1038/aps.2011.64.

Calcium binding protein-mediated regulation of voltage-gated calcium channels linked to human diseases.

Author information

1
Department of Physiology, Faculty of Medicine, University of Toronto, 3306 MSB, 1 King's College Circle, Toronto, Ontario, Canada.

Abstract

Calcium ion entry through voltage-gated calcium channels is essential for cellular signalling in a wide variety of cells and multiple physiological processes. Perturbations of voltage-gated calcium channel function can lead to pathophysiological consequences. Calcium binding proteins serve as calcium sensors and regulate the calcium channel properties via feedback mechanisms. This review highlights the current evidences of calcium binding protein-mediated channel regulation in human diseases.

PMID:
21642945
PMCID:
PMC4009971
DOI:
10.1038/aps.2011.64
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Nature Publishing Group Icon for PubMed Central
    Loading ...
    Support Center