[Changes in the secretion of the hormones of the hypothalamo-hypophyseo-adrenal system in Itsenko-Cushing disease under the influence of insulin-induced hypoglycemia and thyroliberin]

Vrach Delo. 1990 Mar:(3):72-5.
[Article in Russian]

Abstract

The concentration of corticotropin and cortisol in the blood was determined 120 patients with Itsenko-Cushing radioimmunologically after insulin hypoglycemia, after administration of insulin and thyroliberin. It was established that healthy persons and patients with Itsenko-Cushing disease showed no differences in the effect of insulin and thyroliberin as compared with insulin hypoglycemia on the state of the pituitary-adrenal system.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adrenocorticotropic Hormone / blood
  • Adrenocorticotropic Hormone / drug effects
  • Adrenocorticotropic Hormone / metabolism*
  • Adult
  • Cushing Syndrome / blood*
  • Cushing Syndrome / drug therapy
  • Cyproheptadine / therapeutic use
  • Fasting
  • Humans
  • Hydrocortisone / blood
  • Hydrocortisone / metabolism*
  • Hypoglycemia / blood
  • Hypoglycemia / chemically induced*
  • Insulin*
  • Middle Aged
  • Mitotane / therapeutic use
  • Thyrotropin-Releasing Hormone*
  • Time Factors

Substances

  • Insulin
  • Cyproheptadine
  • Thyrotropin-Releasing Hormone
  • Mitotane
  • Adrenocorticotropic Hormone
  • Hydrocortisone