Format

Send to

Choose Destination
See comment in PubMed Commons below
Eur J Obstet Gynecol Reprod Biol. 2011 Oct;158(2):141-7. doi: 10.1016/j.ejogrb.2011.04.040. Epub 2011 Jun 2.

Essential thrombocythemia and pregnancy.

Author information

1
INSERM, U1048, Université Toulouse 3, I2MC, Equipe 9, CHU-Rangueil, Avenue Jean Poulhès BP84225, 31432 Toulouse Cedex 04, France.

Abstract

Essential thrombocythaemia (ET) is an acquired myeloproliferative neoplasm, characterised by persistent thrombocytosis and a tendency for either thrombosis or haemorrhage. Among myeloproliferative neoplasms, ET is the most prevalent in young women, which constitute a special group due to their childbearing potential. An increased risk of fetal and maternal complications has been demonstrated in patients with ET. The most common pregnancy-related complication is spontaneous abortion during the first trimester. Recurrent abortion, fetal growth restriction, stillbirth and placental abruption are less frequent. Maternal complications are relatively rare and essentially represented by thromboembolic and bleeding events. Here we summarize the literature describing pregnancy and its outcome in patients with ET and discuss some recommendations for the management of pregnancy.

PMID:
21640467
DOI:
10.1016/j.ejogrb.2011.04.040
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Elsevier Science
    Loading ...
    Support Center