Send to

Choose Destination
See comment in PubMed Commons below
Am J Orthop (Belle Mead NJ). 2010 Nov;39(11):525-30.

Remodeling and repair of orthopedic tissue: role of mechanical loading and biologics.

Author information

McKay Orthopaedic Research Laboratory, Department of Orthopaedic Surgery, and Bioengineering Department, School of Engineering and Applied Science, University of Pennsylvania, Philadelphia, USA.


Orthopedic tissues respond to mechanical loads to maintain normal homeostasis and in response to injury. As the body of work on this continues to grow, it is important to synthesize the recent studies across tissues and specialties with one another and with past studies. Hence, this review highlights the knowledge gained since 2000, with only few exceptions, concerning the effects of mechanical load and biologics on remodeling and repair of orthopedic tissue.

[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Loading ...
    Support Center