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Anesthesiol Clin. 2011 Jun;29(2):233-42. doi: 10.1016/j.anclin.2011.04.007.

Local anesthetic systemic toxicity: prevention and treatment.

Author information

1
Department of Anesthesiology, University of Illinois at Chicago, 3200 West UICH MC 515, 1740 West Taylor Street, Chicago, IL 60612, USA. Pmerca1@uic.edu

Abstract

Anesthesia is a sine qua non for most surgeries. Like any medical advance, progress in regional anesthesia has not come without its share of complications, including a spectrum extending from localized nerve injury to systemic cardiovascular toxicity and death. This article discusses the mechanisms and clinical presentation, prevention, treatment, and future trends of local anesthetic systemic toxicity. The adverse effects of lipid emulsion therapy are also included.

PMID:
21620340
DOI:
10.1016/j.anclin.2011.04.007
[Indexed for MEDLINE]

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