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Epilepsy Behav. 2011 Jul;21(3):324-6. doi: 10.1016/j.yebeh.2011.04.058. Epub 2011 May 25.

Gabapentin-induced sexual dysfunction.

Author information

1
Department of Psychiatry, UMDNJ-Robert Wood Johnson Medical School, New Brunswick, NJ, USA. kaufmakr@umdnj.edu

Abstract

Sexual dysfunction is a key adverse effect leading to medication noncompliance. Psychotropic drugs associated with sexual dysfunction include antiepileptic drugs, antidepressants, and antipsychotics. Gabapentin, frequently used off-label to treat psychiatric and pain disorders, has previously been reported to cause sexual dysfunction at a minimum total daily dose of 900 mg. This report addresses dose-dependent gabapentin-induced sexual dysfunction reaching total sexual dysfunction (loss of libido, anejaculation, anorgasmia, and impotence) at a total daily dose of only 300 mg.

PMID:
21612983
DOI:
10.1016/j.yebeh.2011.04.058
[Indexed for MEDLINE]

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