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World J Gastrointest Pathophysiol. 2011 Apr 15;2(2):26-30. doi: 10.4291/wjgp.v2.i2.26.

Primary hepatic gastrinoma: Report of a case and review of literature.

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Konstantinos Tsalis, Georgios Vrakas, Abraham Dimoulas, Charalampos Lazarides, Fourth Surgical Department, Aristotle University, Thessaloniki 57010, Greece.


Primary hepatic gastrinoma is a very rare ectopic gastrinoma with less than 20 cases reported worldwide. We report the case of a patient with hypergastrinemia who was subjected to exhaustive preoperative and intraoperative imaging and also careful surgical exploration of the duodenum and pancreas which failed initially to identify the primary tumour. Eventually the patient was subjected to left liver lobectomy, as a small palpable lesion was noted intraoperatively. The diagnosis of gastrinoma requires a high index of clinical suspicion and the flawless cooperation of many specialties.


Primary hepatic gastrinoma; Zollinger-Ellison syndrome

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