Format

Send to

Choose Destination
See comment in PubMed Commons below
World J Gastrointest Pathophysiol. 2010 Jun 15;1(2):38-49. doi: 10.4291/wjgp.v1.i2.38.

Histamine regulation of hyperplastic and neoplastic cell growth in cholangiocytes.

Author information

  • 1Paolo Onori, Experimental Medicine, University of L'Aquila, L'Aquila 67100, Italy.

Abstract

Histamine has long been known to be involved in inflammatory events. The discovery of antihistamines dates back to the first half of the 20(th) century when a Swiss-Italian pharmacologist, Daniel Bovet began his work. In 1957 he was awarded a Nobel Prize for his production of antihistamines for allergy relief. Since that time, histamine has been found to play a role in other events besides allergic reaction. Possibly unbelievable to Bovet and his peers, histamine has now been marked as playing a role in liver pathologies including hepatobiliary diseases.

KEYWORDS:

Cholangiocarcinoma; Cholangiocytes; Cholestasis; Histamine; Receptors

PMID:
21607141
PMCID:
PMC3097946
DOI:
10.4291/wjgp.v1.i2.38
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Baishideng Publishing Group Inc. Icon for PubMed Central
    Loading ...
    Support Center