Format

Send to

Choose Destination
See comment in PubMed Commons below
Expert Rev Vaccines. 2011 May;10(5):605-15. doi: 10.1586/erv.11.60.

Review of diphtheria, tetanus and pertussis vaccines in clinical development.

Author information

1
Pfizer Ltd, Vanwall Road, Maidenhead, Berkshire, SL6 4UB, UK. nicholas.kitchin@pfizer.com

Abstract

Diphtheria, tetanus and pertussis vaccines have formed the cornerstone of childhood immunization programs for decades. Historically, these have comprised diphtheria and tetanus toxoids combined with inactivated whole-cell pertussis. More recently, advances have been made with the development of purified acellular pertussis vaccines, with improved reactogenicity profiles, and formulation with additional vaccines such as Haemophilus influenzae type b, hepatitis B virus and inactivated poliovirus. Development is currently focused on maximizing the number of vaccines that can be combined in a single formulation and strategies to provide protection against pertussis before the commencement of routine infant immunization.

PMID:
21604982
DOI:
10.1586/erv.11.60
[Indexed for MEDLINE]
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Taylor & Francis
    Loading ...
    Support Center