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Ann Med. 2011;43(6):487-94. doi: 10.3109/07853890.2011.554428. Epub 2011 May 23.

The Finnish Diabetes Risk Score (FINDRISC) as a screening tool for hepatic steatosis.

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1
Preventive Medicine Center Hospital Israelita Albert Einstein, Sao Paulo, Brazil.

Abstract

INTRODUCTION:

Hepatic steatosis due to non-alcoholic fatty liver disease is associated with obesity, dyslipidemia, insulin resistance, and type 2 diabetes. The Finnish Diabetes Risk Score (FINDRISC) is a prognostic screening tool to detect people at risk for type 2 diabetes without the use of any blood test. The objective of this study was to evaluate whether FINDRISC can also be used to screen for the presence of hepatic steatosis.

PATIENTS AND METHODS:

Steatosis was determined by ultrasound. The study sample consisted of 821 non-diabetic subjects without previous hepatic disease; 81% were men (mean age 45 ± 9 years) and 19% women (mean age 41 ± 10 years).

RESULTS:

Steatosis was present in 44% of men and 10% of women. The odds ratio for one unit increase in the FINDRISC associated with the risk of steatosis was 1.30 (95% CI 1.25-1.35), similar for men and women. The area under the receiver operating characteristics curve for steatosis was 0.80 (95% CI 0.77-0.83); 0.80 in men (95% CI 0.77-0.83) and 0.83 (95% CI 0.73-0.93) in women.

CONCLUSIONS:

Our data suggest that the FINDRISC could be a useful primary screening tool for the presence of steatosis.

PMID:
21604917
DOI:
10.3109/07853890.2011.554428
[Indexed for MEDLINE]

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