Send to

Choose Destination
See comment in PubMed Commons below
J Neurogastroenterol Motil. 2011 Apr;17(2):140-7. doi: 10.5056/jnm.2011.17.2.140. Epub 2011 Apr 27.

Microflora modulation of motility.

Author information

Alimentary Pharmabiotic Centre, University College Cork, Cork, Ireland.


That gastrointestinal motility can influence the gut microbiota has been known for decades and the clinical consequences of impaired motility, in terms of the bacterial population of the small intestine, amply illustrated by the syndrome of small intestinal bacterial overgrowth which so commonly accompanies diffuse intestinal motility disorders. As the importance of the microbiota to homeostasis in health and to a variety of disease states is increasingly appreciated and as the full diversity and biology of this "hidden organ" have been revealed by molecular methodologies, the true nature of the interaction between the microbiota and motility is being re-examined and the complexity of this relationship exposed. In health, as well as in disease states, this is a truly bi-directional relationship: not only can gut motor patterns influence the microbiota but changes in the microbiota can exert profound influences on gut sensori-motor function.


Gastrointestinal motility; Irritable bowel syndrome; Metagenome

PubMed Commons home

PubMed Commons

How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for Inforang Icon for PubMed Central
    Loading ...
    Support Center