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Ocul Immunol Inflamm. 2011 Jun;19(3):214-5. doi: 10.3109/09273948.2011.553980.

Use of a high infusion rate to prevent posterior dislocation of fluocinolone acetonide implant during surgical removal.

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1
University of California, San Francisco, Department of Ophthalmology, San Francisco, California 94143-0730, USA.

Abstract

PURPOSE:

To describe a strategy for reducing the risk of posterior dislocation of a fluocinolone implant during exchange or removal.

DESIGN:

Case report and in vitro model.

METHODS:

Description of a surgical case and an in vitro experiment evaluating the role of infusion pressure in maintaining implant stability in surgery.

RESULTS:

Use of an elevated infusion pressure allowed safe removal of a fluocinolone implant that spontaneously dissociated into two pieces during removal. An in vitro model using the implant's drug reservoir in a cadaver eye demonstrated that the implant remained in a stable location at the scleral incision if the infusion pressure was high, whereas with a lower infusion pressure the implant spontaneously fell onto the posterior pole of the eye.

CONCLUSIONS:

During exchange or removal of a fluocinolone implant, an elevated infusion pressure may reduce the risk of posterior dislocation of the device.

PMID:
21595540
DOI:
10.3109/09273948.2011.553980
[Indexed for MEDLINE]
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