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Dermatol Surg. 2011 Aug;37(8):1133-40. doi: 10.1111/j.1524-4725.2011.02018.x. Epub 2011 May 17.

Efficacy of 694-nm Q-switched ruby fractional laser treatment of melasma in female Korean patients.

Author information

1
Department of Dermatology, College of Medicine, Chung-Ang University, Seoul, Korea.

Abstract

BACKGROUND:

Melasma is a common acquired symmetrical hypermelanosis of sun-exposed areas of the skin. Although the classical Q-switched ruby laser (QSRL) has been used successfully for the removal of tattoos and for the treatment of cutaneous pigmented lesions, its efficacy for melasma remains controversial.

OBJECTIVE:

We used repeat low-dose fractional QSRL treatment for melasma and analyzed the clinical results.

METHODS:

Fifteen Korean women with melasma were enrolled. Each patient received six low-dose fractional QSRL treatments to the face at 2-week intervals. Two investigators independently evaluated Melasma Area and Severity Index (MASI) scores before each session and 4 and 16 weeks after the final session. The intensities of pigmentation and erythema were assessed by measuring skin reflectance using a tristimulus color analyzer.

RESULTS:

Mean MASI score decreased from 15.1 ± 3.3 before treatment to 10.6 ± 3.9 16 weeks after the final treatment. The lightness of pigmentation (L-value) increased from 56.6 ± 3.5 before treatment to 59.9 ± 2.8 16 weeks after the final treatment.

CONCLUSIONS:

Multiple treatment sessions of low-dose fractional QSRL may be an effective strategy for the treatment of dermal or mixed-type melasma.

[Indexed for MEDLINE]

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