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Can J Ophthalmol. 1990 Feb;25(1):38-41.

Painful ophthalmoplegia caused by neurotropic malignant melanoma.

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1
Department of Ophthalmology, Yale University School of Medicine, New Haven, Connecticut.

Abstract

Progressive cranial nerve palsies and painful ophthalmoplegia developed in a 76-year-old man with lentigo maligna of the forehead 18 months after the excision of a spindle cell tumour of the forehead that proved on immunohistochemical study to be a malignant melanoma. The signs and symptoms were caused by neurotropic spread of the malignant melanoma into the cavernous sinus and subsequent neurosarcomatous transformation of the orbital metastasis.

PMID:
2158383
[Indexed for MEDLINE]
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