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Trends Biochem Sci. 1990 Mar;15(3):98-102.

Okadaic acid: a new probe for the study of cellular regulation.

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  • 1Department of Biochemistry, University of Dundee, UK.

Abstract

The tumour promoter okadaic acid is a potent and specific inhibitor of protein phosphatases 1 and 2A. Here we review recent studies which demonstrate that this toxin is extremely useful for identifying biological processes that are controlled through the reversible phosphorylation of proteins.

PMID:
2158158
[PubMed - indexed for MEDLINE]
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