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Zhongguo Dang Dai Er Ke Za Zhi. 2011 May;13(5):388-91.

[Risk factors for patent ductus arteriosus in neonates].

[Article in Chinese]

Author information

1
Department of Pediatrics, West China Second University Hospital, Sichuan University, Chengdu 610041, China.

Abstract

OBJECTIVE:

To identify the risk factors for patent ductus arteriosus (PDA) in neonates.

METHODS:

Fifty infants with PDA and 100 infants without PDA were enrolled. Chi-square test, Student's t test and the linear correlation analysis were used to study the clinical data. Logistic regression analysis was used to investigate the independent risk factors for PDA.

RESULTS:

The prevalence of PDA was negatively correlated with the gestation age (r=-0.03, P<0.05) and birth weight (r=-0.04, P<0.05). Oxygen inhalation was a protective factor for the development of PDA. Fetal distress, meconium-stained amniotic fluid, oligohydramnios, cord entanglement, 1 minute Apgar score <8, maternal infection and hypoxic-ischemic encephalopathy were the independent risk factors for the development of PDA.

CONCLUSIONS:

The incidence of PDA can be reduced by preventing maternal infection, premature birth, low birth weight and hypoxia.

PMID:
21575344
[Indexed for MEDLINE]

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