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BMC Pulm Med. 2011 May 13;11:23. doi: 10.1186/1471-2466-11-23.

A crossover study of short burst oxygen therapy (SBOT) for the relief of exercise-induced breathlessness in severe COPD.

Author information

1
Manchester Academic Health Science Centre, University of Manchester, Salford Royal University Hospital, Stott Lane, Salford M6 8HD, UK. ronan.o.driscoll@srft.nhs.uk

Abstract

BACKGROUND:

Previous small studies suggested SBOT may be ineffective in relieving breathlessness after exercise in COPD.

METHODS:

34 COPD patients with FEV1 <40% predicted and resting oxygen saturation ≥93% undertook an exercise step test 4 times. After exercise, patients were given 4 l/min of oxygen from a simple face mask, 4 l/min air from a face mask (single blind), air from a fan or no intervention.

RESULTS:

Average oxygen saturation fell from 95.0% to 91.3% after exercise. The mean time to subjective recovery was 3.3 minutes with no difference between treatments. The mean Borg breathlessness score was 1.5/10 at rest, rising to 5.1/10 at the end of exercise (No breathlessness = 0, worst possible breathlessness = 10). Oxygen therapy had no discernable effect on Borg scores even for 14 patients who desaturated below 90%. 15 patients had no preferred treatment, 7 preferred oxygen, 6 preferred the fan, 3 preferred air via a mask and 3 preferred room air.

CONCLUSIONS:

This study provides no support for the idea that COPD patients who are not hypoxaemic at rest derive noticeable benefit from oxygen therapy after exercise. Use of air from a mask or from a fan had no apparent physiological or placebo effect.

PMID:
21569473
PMCID:
PMC3117831
DOI:
10.1186/1471-2466-11-23
[Indexed for MEDLINE]
Free PMC Article

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