Format

Send to

Choose Destination
See comment in PubMed Commons below
ACS Nano. 2011 Jun 28;5(6):4704-11. doi: 10.1021/nn2006128. Epub 2011 May 13.

Polarization-controlled differentiation of human neural stem cells using synergistic cues from the patterns of carbon nanotube monolayer coating.

Author information

1
Interdisciplinary Program in Nano-Science and Technology, Seoul National University, Seoul 151-747, Korea.

Abstract

We report a method for selective growth and structural-polarization-controlled neuronal differentiation of human neural stem cells (hNSCs) into neurons using carbon nanotube network patterns. The CNT patterns provide synergistic cues for the differentiation of hNSCs in physiological solution and an optimal nanotopography at the same time with good biocompatibility. We demonstrated a polarization-controlled neuronal differentiation at the level of individual NSCs. This result should provide a stable and versatile platform for controlling the hNSC growth because CNT patterns are known to be stable in time unlike commonly used organic molecular patterns.

PMID:
21568294
PMCID:
PMC3125501
DOI:
10.1021/nn2006128
[Indexed for MEDLINE]
Free PMC Article
PubMed Commons home

PubMed Commons

0 comments
How to join PubMed Commons

    Supplemental Content

    Full text links

    Icon for American Chemical Society Icon for PubMed Central
    Loading ...
    Support Center