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Open Dent J. 2011 Apr 13;5:66-70. doi: 10.2174/1874210601105010066.

Oral inflammatory myofibroblastic tumor: case report and review of literature.

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  • 1Department of Oncology and Diagnostic Sciences, Dental School, University of Maryland, Baltimore, USA.


Inflammatory myofibroblastic tumor (IMT) is a rarely described tumor of unknown etiology and pathogenesis. It occurs primarily in the lungs, but has occurred in other extra-pulmonary sites. Histologically these lesions appear as an inflammatory infiltrate within a variably myofibrotic background. Current evidence shows that inflammatory myofibroblastic tumors are neoplastic processes resulting from chromosomal translocations that often cause an overexpression of ALK kinase, which is often assessed using immunohistochemical studies. Currently, the biological behavior of oral inflammatory myofibroblastic tumor is still uncertain. This article describes the clinical, histological, and operative features of a case of IMT of the oral cavity.


Inflammatory myofibroblastic tumor; inflammatory pseudotumor; oral cavity.

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