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Nucleic Acids Res. 2011 Jul;39(Web Server issue):W68-73. doi: 10.1093/nar/gkr316. Epub 2011 May 10.

CURVES+ web server for analyzing and visualizing the helical, backbone and groove parameters of nucleic acid structures.

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Université Lyon 1, CNRS, UMR 5086, Bases Moléculaires et Structurales des Systèmes Infectieux, IBCP FR3302, 7 passage du Vercors, F-69367, France.


Curves+, a revised version of the Curves software for analyzing the conformation of nucleic acid structures, is now available as a web server. This version, which can be freely accessed at, allows the user to upload a nucleic acid structure file, choose the nucleotides to be analyzed and after optionally setting a number of input variables, view the numerical and graphic results online or download files containing a set of helical, backbone and groove parameters that fully describe the structure. PDB format files are also provided for offline visualization of the helical axis and groove geometry.

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