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Hum Exp Toxicol. 2011 Dec;30(12):2027-30. doi: 10.1177/0960327111408153. Epub 2011 May 9.

Hormesis, resveratrol and plant-derived polyphenols: some comments.

Abstract

Hormesis is a dose-response phenomenon, usually present in plants and animals, characterized by a low-dose stimulation and high-dose inhibition, often resulting in typical U-shaped or J-shaped curves. Hormesis has become an interesting model for toxicology and risk assessment, as it has been described for several nature-derived phytochemicals but also because this adaptive response to stressors might hide an underlying more general behaviour of cell towards low doses.

PMID:
21558146
DOI:
10.1177/0960327111408153
[Indexed for MEDLINE]

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