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Singapore Med J. 2011 Apr;52(4):299-302.

The perils of medical tourism: NDM-1-positive Escherichia coli causing febrile neutropenia in a medical tourist.

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Department of Haematology-Oncology, National Univeristy Hospital, 1E Lower Kent Ridge Road, NUHS Tower Block Level 7, Singapore 119228.


NDM-1 is a new metallo-beta-lactamase that readily hydrolyses carbapenems, penicillins and cephalosporins. Its rising incidence has been reported in many countries around the world, with many cases linked to a possible origin from the Indian subcontinent. Due to the lack of effective antibiotic regimes to treat these infections, the increased prevalence of NDM-1 is alarming. We describe a case of NDM-1 infection in an immunocompromised foreign patient, and discuss its implications.

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