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Science. 2011 May 27;332(6033):1097-100. doi: 10.1126/science.1203980. Epub 2011 May 5.

Deciphering the rhizosphere microbiome for disease-suppressive bacteria.

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1
Laboratory of Phytopathology, Wageningen University, Droevendaalsesteeg 1, Wageningen 6700 EE, Netherlands.

Abstract

Disease-suppressive soils are exceptional ecosystems in which crop plants suffer less from specific soil-borne pathogens than expected owing to the activities of other soil microorganisms. For most disease-suppressive soils, the microbes and mechanisms involved in pathogen control are unknown. By coupling PhyloChip-based metagenomics of the rhizosphere microbiome with culture-dependent functional analyses, we identified key bacterial taxa and genes involved in suppression of a fungal root pathogen. More than 33,000 bacterial and archaeal species were detected, with Proteobacteria, Firmicutes, and Actinobacteria consistently associated with disease suppression. Members of the γ-Proteobacteria were shown to have disease-suppressive activity governed by nonribosomal peptide synthetases. Our data indicate that upon attack by a fungal root pathogen, plants can exploit microbial consortia from soil for protection against infections.

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PMID:
21551032
DOI:
10.1126/science.1203980
[Indexed for MEDLINE]
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