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Curr Biol. 2011 May 10;21(9):R320-30. doi: 10.1016/j.cub.2011.02.045.

Two-component systems and their co-option for eukaryotic signal transduction.

Author information

1
Department of Biological Sciences, Dartmouth College, Hanover, NH 03755, USA. george.e.schaller@dartmouth.edu

Abstract

Two-component signaling pathways involve histidine kinases, response regulators, and sometimes histidine-containing phosphotransfer proteins. Prevalent in prokaryotes, these signaling elements have also been co-opted to meet the needs of signal transduction in eukaryotes such as fungi and plants. Here we consider the evolution of such regulatory systems, with a particular emphasis on the roles they play in signaling by the plant hormones cytokinin and ethylene, in phytochrome-mediated perception of light, and as integral components of the circadian clock.

PMID:
21549954
DOI:
10.1016/j.cub.2011.02.045
[Indexed for MEDLINE]
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