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J Investig Allergol Clin Immunol. 2011;21(3):162-70; quiz 2 p following 170.

Cross-reactivity syndromes in food allergy.

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Servicio de Alergología, Complejo Hospitalario de Navarra, Centro de Salud Conde Oliveto, Pamplona, Spain.


The immunological phenomenon of cross-reactivity has consequences for the diagnosis and treatment of certain food allergies. Once allergy to a particular food has been confirmed, positive test results are often obtained against other foods and, although less frequently, true clinical cross-reactivity is determined. This article reviews the relevant clinical aspects of food allergies in which the underlying mechanism is cross-reactivity between foods that are both related and unrelated taxonomically.

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