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Arch Pharm Res. 2011 Mar;34(3):419-23. doi: 10.1007/s12272-011-0309-7. Epub 2011 May 6.

Inhibitory activity of Plantago major L. on angiotensin I-converting enzyme.

Author information

1
College of Pharmacy, Chungnam National University, Daejeon, Korea.

Abstract

Eight compounds were isolated from methanol extract of Plantago major L. leaves and investigated for their ability to inhibit angiotensin I-converting enzyme activity. Among them, compound 1 showed the most potent inhibition with rate of 28.06 ± 0.21% at a concentration of 100 μM. Compounds 2 and 8 exhibited weak activities. These results suggest that compound 1 might contribute to the ability of P. major to inhibit the activity of angiotensin I- converting enzyme.

PMID:
21547673
DOI:
10.1007/s12272-011-0309-7
[Indexed for MEDLINE]

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