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World J Gastroenterol. 2011 Apr 28;17(16):2104-8. doi: 10.3748/wjg.v17.i16.2104.

Dietary treatment of colic caused by excess gas in infants: biochemical evidence.

Author information

1
Unit of Gastroenterology, Hepatology and Nutrition, Children's Hospital Vall d'Hebron, Autonomous University, Barcelona 08035, Spain. dinfante@terra.es

Abstract

AIM:

To evaluate the impact of feeding colicky infants with an adapted formula on the hydrogen breath test and clinical symptoms.

METHODS:

Hydrogen expiration was measured by SC MicroLyzer gas chromatography at inclusion and 15 d after treatment with an adapted low-lactose formula in 20 colicky infants.

RESULTS:

All babies were symptomatic: 85% with excess gas, 75% with abnormal feeding pattern, and 85% with excessive crying. The hydrogen breath test at inclusion was abnormal: 35 ± 3.1 ppm. After 15 d feeding with an adapted low-lactose formula, crying and flatulence decreased in 85% of patients (P < 0.001). For infants in whom no decrease of gas was reported, crying was still reduced (P < 0.01). Moreover, the feeding pattern was improved in 50% of infants when it was initially considered as abnormal. Finally, the hydrogen breath test decreased significantly (10 ± 2.5 ppm, P < 0.01).

CONCLUSION:

This study showed an association between clinical improvement and evidence of decreased levels of hydrogen when the infants were fed with a specially designed, low-lactose formula.

KEYWORDS:

Colic; Hydrogen breath test; Infants; Lactose

PMID:
21547129
PMCID:
PMC3084395
DOI:
10.3748/wjg.v17.i16.2104
[Indexed for MEDLINE]
Free PMC Article

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