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J Perinatol. 2012 Jan;32(1):51-4. doi: 10.1038/jp.2011.50. Epub 2011 May 5.

The effect of late preterm birth on mortality of infants with major congenital heart defects.

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1
Department of Pediatrics and Communicable Diseases, University of Michigan Health System, Ann Arbor, MI, USA.

Abstract

OBJECTIVE:

We evaluated the effect of late preterm delivery (34 to 36 weeks) on hospital mortality of infants with congenital heart defects (CHDs).

STUDY DESIGN:

Retrospective record review of infants with major CHD born at or after to 34 weeks, cared for in a single tertiary perinatal center between 2002 and 2009. Factors associated with death before discharge from the hospital were ascertained using univariate and multivariate analyses.

RESULT:

Of the 753 infants with CHD, 117 were born at late preterm. Using logistic regression analysis, white race (OR; 95% CI) (0.60; 0.39 to 0.95), late preterm delivery (2.70; 1.69 to 4.33), and need for intubation in the delivery room (3.15; 1.92 to 5.17) were independently associated with hospital death.

CONCLUSION:

Late preterm birth of infants with major CHDs was independently associated with increased risk of hospital death compared with delivery at more mature gestational ages.

PMID:
21546940
DOI:
10.1038/jp.2011.50
[Indexed for MEDLINE]
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