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J Bras Pneumol. 2011 Mar-Apr;37(2):272-6.

Treatment of schistosomiasis-associated pulmonary hypertension.

[Article in English, Portuguese]

Author information

1
Department of Pulmonology and Thoracic Surgery, Federal University of Minas Gerais School of Medicine, Belo Horizonte, Brazil. racorrea9@gmail.com

Abstract

Schistosomiasis mansoni is the third most prevalent endemic parasitic disease in the world. It is estimated that over 200 million people are infected with parasites belonging to one of the Schistosoma species. Of those, 270,000 people (4.6%) suffer from pulmonary arterial hypertension, which is associated with the hepatosplenic form of the disease. This high prevalence makes schistosomiasis-associated pulmonary hypertension the leading cause of pulmonary hypertension worldwide. However, no specific treatment for the pulmonary vascular component of the disease has yet been devised. We report the case of a patient with schistosomiasis-associated pulmonary hypertension who was treated satisfactorily with a phosphodiesterase-5 inhibitor (sildenafil).

PMID:
21537664
DOI:
10.1590/s1806-37132011000200018
[Indexed for MEDLINE]
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