Format

Send to

Choose Destination
Spinal Cord. 2011 Sep;49(9):1014-9. doi: 10.1038/sc.2011.41. Epub 2011 May 3.

Transdermal nitroglycerine treatment of shoulder tendinopathies in patients with spinal cord injuries.

Author information

1
Department of Physical Medicine and Rehabilitation (Spinal Cord Injury Unit), Hospital La Fe, Valencia, Spain.

Abstract

STUDY DESIGN:

A clinical blind study was conducted to determine the efficacy of transdermal nitroglycerine treatment on the awareness of shoulder pain.

OBJECTIVE:

This study aims to determine the effects of transdermal nitroglycerine on shoulder pain and on functional shoulder movement in patients with spinal cord injuries and shoulder tendinopathies. A second aim is to establish the side effects of the treatment.

SETTING:

Hospital "La Fe" in Valencia, Spain.

METHODS:

A total of 45 spinal cord injury patients, all of whom are wheelchair users with shoulder tendinopathy, were randomly divided into two groups: placebo (n=12) and experimental (n=33). The experimental group (EG) received transdermal treatment for 6 months in the form of a 1.25 mg nitroglycerine (NT) patch on the greater tubercle. A placebo patch was used with the placebo subjects. Functional shoulder movements were assessed by articular range of motion and pain, using a visual analogical scale.

RESULTS:

NT treatment reduced the awareness of shoulder pain and increased the functional movement and range of articular motion in the shoulders of the EG members (P<0.05).

CONCLUSIONS:

We conclude that transdermal NT is an efficient method for treating shoulder tendinopathies in wheelchair users with spinal cord injuries.

PMID:
21537337
DOI:
10.1038/sc.2011.41
[Indexed for MEDLINE]

Supplemental Content

Full text links

Icon for Nature Publishing Group
Loading ...
Support Center