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J Struct Biol. 2011 Aug;175(2):244-52. doi: 10.1016/j.jsb.2011.04.011. Epub 2011 Apr 23.

Proteopedia: a status report on the collaborative, 3D web-encyclopedia of proteins and other biomolecules.

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Bioinformatics Unit, Biological Services Unit, Weizmann Institute of Science, Rehovot 76100, Israel.


Proteopedia is a collaborative, 3D web-encyclopedia of protein, nucleic acid and other biomolecule structures. Created as a means for communicating biomolecule structures to a diverse scientific audience, Proteopedia ( presents structural annotation in an intuitive, interactive format and allows members of the scientific community to easily contribute their own annotations. Here, we provide a status report on Proteopedia by describing advances in the web resource since its inception three and a half years ago, focusing on features of potential direct use to the scientific community. We discuss its progress as a collaborative 3D-encyclopedia of structures as well as its use as a complement to scientific publications and PowerPoint presentations. We also describe Proteopedia's use for 3D visualization in structure-related pedagogy.

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